Category: Uncategorized

  • What Is 5-Amino-1MQ? A Research Overview of NNMT Inhibition and NAD⁺ Metabolism

    What Is 5-Amino-1MQ? A Research Overview of NNMT Inhibition and NAD⁺ Metabolism

    Introduction 5-Amino-1MQ (5-amino-1-methylquinolinium) is a synthetic small molecule of growing scientific interest for its role as a nicotinamide N-methyltransferase (NNMT) inhibitor. NNMT is a cytosolic enzyme that catalyzes the methylation of nicotinamide (NAM), a key substrate in the NAD⁺ salvage pathway. By inhibiting NNMT activity, 5-Amino-1MQ has been explored in laboratory models for its ability…

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